A newly-engaged couple have a breakdown in an isolated area and must seek shelter at the bizarre residence of Dr. Frank-n-Furter.

On a wild and rain-swept late-November evening, somewhere at an empty stretch of road outside Ohio's merry Denton, blissfully-affianced, prudish, boringly-innocent young pair Brad Majors (Barry Bostwick) and Janet Weiss (Susan Sarandon) find themselves stranded on their way to visit an ex-tutor. Instead, the couple will inadvertently unearth the cross-dressing Dr. Frank-N-Furter's (Tim Curry's) spooky lair of inexhaustible oddities, just in time to partake in the out-of-this-world mad scientist's proud unveiling of his latest, delightfully extravagant, most daring creation: the ultimate male and the perfect sex symbol: the flaxen-haired Rocky Horror (Peter Hinwood). But, little by little, as the effervescent transgressive force gobbles up whole the unsuspecting visitors of the night, Brad and Janet slowly begin to embrace the potent fascinations of seduction, while an idolized Rocky roams free in the mansion. Who can interrupt man's union with the absolute pleasure?